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These blood cancers share similarities, but differ in significant ways:

Non-Hodgkin lymphoma is more common than Hodgkin lymphoma.
Different lymphocytes are involved in these lymphomas. The hallmark of Hodgkin lymphoma is the presence of abnormalities called Reed-Sternberg cells, which are not present in non-Hodgkin lymphoma.
Hodgkin lymphoma often occurs in people under 40, while non-Hodgkin lymphoma is more common in people over 60.

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